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Variant H1N2 Influenza Diagnosed in Pennsylvania


The Pennsylvania Department of Health confirmed that two teenage patients were infected with influenza H1N2v during late June.  One patient required hospitalization.  Infection was acquired from contact with hogs at a livestock auction.  Investigations failed to confirm human-to-human contact.


 Animal-associated influenza viruses that infect humans are designated variants (v).  Based on previous cases, these influenza isolates have limited ability to infect humans and are unlikely to become contagious.  It is, however, necessary to characterize variant influenza viruses and determine through whole genome sequencing whether mutations have occurred that could affect infectivity or pathogenicity.